The nucleus contains DNA, which is essential for cell division and repair. Since RBCs have no nucleus:
They cannot divide.
They cannot repair themselves.
They have a limited lifespan—about 120 days.
Despite this, they survive because:
They are pre-built and loaded with all the machinery (enzymes, hemoglobin, membrane proteins) they need before they lose their nucleus.
They rely on anaerobic glycolysis (breakdown of glucose without oxygen) for energy, since they don’t have mitochondria either.
They cannot divide.
They cannot repair themselves.
They have a limited lifespan—about 120 days.
Despite this, they survive because:
They are pre-built and loaded with all the machinery (enzymes, hemoglobin, membrane proteins) they need before they lose their nucleus.
They rely on anaerobic glycolysis (breakdown of glucose without oxygen) for energy, since they don’t have mitochondria either.
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